From the three types of marijuana, it is the hybrid which allows for the making of different ratios of CBD to THC levels. These ratios work differently in each individual, but in a general sense, both THC and CBD have the previously described effects.

An example of this may be two individuals could have epilepsy and the same seizure type, and a specific concentration help one while having no effect on the other individual. Because of this, it is difficult to know what specifically will work for ones’ condition, and different concentrations may have to be tried before finding what works best for the individual.

The strain of CBD has been shown to be more effective in the treatment of seizures than THC. The exact reason for this is still not totally clear. One general reason for a reduction in seizures seen could be from a decrease in anxiety and depression which one may have.

Numerous studies have shown that conditions such as depression and anxiety act as triggers for both epileptic seizures and non epileptic events which mimic seizures. These are known as PNES or psychogenic non epileptic seizures.

Some different reasons for marijuana having a positive effect on seizures include: The antagonism of G-protein coupled receptors and inhibition of andonsine re uptake.(2). Other possible reasons for this include the targeting of abnormal sodium channels, blocking T-type calcium channels and modulation of aderoid receptors. (1)