How does it work ?

How does it work ?

Here you'll find resources on the use of medical marijuana and how it works in treating epillepsy.

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Top rated research facilities

Top rated research facilities

Here are some of the highest quality treatment facilities for individuals with epilepsy.

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Clinical Trials

Clinical Trials

Here you'll find any medical trial that is taking place which you may be eligable for with your doctors conscent.

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What Is Marijuana

Marijuana is another name for the cannabis plant. There are numerous strains and types of cannabis, some which are stronger than others.  Marijuana has been used for years for the treatment of numerous medical conditions. It is currently considered a schedule one substance which has no medical value. Current research shows that the connection between marijuana and epilepsy has promising effects. Here you’ll find information on marijuana and how it can assist in epilepsy and other conditions.  

Types Of Marijuana

Sativa

  • Lower CBD and higher THC levels
  • Helps increase energy and reduce anxiety

Indica

  • Grows faster than saliva
  • Higher CBD and lower THC levels
  • Very relaxing effects

Hybrid

  • Grown in green houses
  • Unique THC to CBD ratio to make different types
  • Decrease anxiety and stress

CBD

Gives a calming and relaxing feeling

Helps psychological conditions like depresion and anxiety

Assists with other medical conditions

Good for use at night

THC

Gives a feeling of euphoria

Better for daytime use

Strains of Marijuana good for epilepsy.

Charlottes Webb

ACDC

Cannatonic

Ringos Gift

Harlequin

Cyber Monday CBD Sale!

 

What Is Epilepsy

Epilepsy is the misfiring of neurotransmitters within the brain. Neurotransmitters transfer the information through neurons from one cell to the next. The main difference between an individual with epilepsy, and someone without is that when a seizure occurs, the frequency of firing of the neurons can be up to ten times as fast as an individual without epilepsy.

Most individuals do not know what a seizure is when they see one. Usually the only type of seizure that someone is able to realize is happening is a total seizure or tonic-clonic seizure. For individuals that are unaware of types of seizures, here are some general descriptions of seizure types.

Tonic

  • The body, arms, or legs may become tense
  • They begin on both sides of the brain but can occur in only one area
  • Usually last less than 20 seconds
  • Person may lose balance

 

Clonic

  • Rare and most commonly seen in babies
  • Jerking movements that may last up to 2 minute

 

Tonic-Clonic

  • What most people think of when they hear the word seizure
  • Loss of consciousness
  • Muscle stiffening
  • Jerking
  • Last usually one to three minutes
  • One lasting more than five minutes should get medical attention

 

Absence seizures

  • Most common type of seizure
  • Individual has a blank stare or look
  • These usually last ten seconds or less
  • Eyes turn upward and flutter

 

Focal awareness

  • Remains alert
  • Able to interact
  • lasts only a few seconds up to two minutes

 

Focal impaired awareness (Complex partial)

  • Usually lasts between one and two minutes
  • Lip smacking
  • Pulling at clothes
  • Wandering

 

Myoclonic

  • Brief shock like jerks to the muscle
  • Individual usually awake and able to function normally
  • Abnormal movements on both sides of body

What Causes A Seizure ?

Chemical Imbalance

 Although it’s not totally known the reason behind seizures occurring, there are two main reasons that have been identified through research. An imbalance of excitable and inhibitory neurotransmitters could be a mechanism. This may include a decrease in the neuro transmitter GABA which is inhibitory (3). Another reason may be a loss of electrical excitability of sodium channels which initiate an action potential in the neurons of the brain (4). These are two of the main physiological actions which may initiate seizures. 

Stress

Numerous studies have also been done on the relationship between anxiety, depression, and how it can trigger a seizure. This should be carefully considered as a possible trigger. There are different types of therapies that can be used to improve this as well.

This can also occur the opposite way as well, with  seizures being a trigger for anxiety and/or depression.  If you think that anxiety or depression may be a trigger for your seizures you should consider using some type of therapy. 

” The prevelance of psychological disstress, especially depression and anxiety disorder, is higher in epilepsy than in other chronic health conditions. These cormorbid features contribute even more than  seizures themselves to impaired quality of life in patients with epilepsy.” (5)

Some conditions that can trigger seizures

  • Anxiety
  • Depression
  • PTSD

Natural therapies 

  • Cognitive behaviorial therapy
  • Mindfulness
  • Meditation

How can marijuana help epilepsy ? 

 

From the three types of marijuana, it is the hybrid which allows for the making of different ratios of CBD to THC levels. These ratios work differently in each individual, but in a general sense, both THC and CBD have the previously described effects.

An example of this may be two individuals could have epilepsy and the same seizure type, and a specific concentration help one while having no effect on the other individual. Because of this, it is difficult to know what specifically will work for ones’ condition, and different concentrations may have to be tried before finding what works best for the individual.

The strain of CBD has been shown to be more effective in the treatment of seizures than THC. The exact reason for this is still not totally clear. One general reason for a reduction in seizures seen could be from a decrease in anxiety and depression which one may have.

Numerous studies have shown that conditions such as depression and anxiety act as triggers for both epileptic seizures and non epileptic events which mimic seizures. These are known as PNES or psychogenic non epileptic seizures.

Some different reasons for marijuana having a positive effect on seizures include: The antagonism of G-protein coupled receptors and inhibition of andonsine re uptake.(2). Other possible reasons for this include the targeting of abnormal sodium channels, blocking T-type calcium channels and modulation of aderoid receptors. (1)

Can CBD help in decreasing seizures ?

The substance of marijuana is currently seen as a schedule 1 drug, meaning that it has no medical use. Some studies have shown CBD, a main substance in marijuana to help with two chronic epilepsy conditions of lennox gastric syndrome (LGS), and dravvett syndrome. There is no known anti epileptic drug which has been shown to help with these conditions.

In the results of these studies, the frequency of seizures was reduced substantially, leading to the approval of a drug for epileptic seizures (Epidiolex). This drug is CBD based since the THC is what causes psychological symptoms like hallucinations and “highs”.

What is PNEE ?

This is short for psychogenic non epileptic events, previously known as PNES, or psychogenic non epileptic seizures. Because the event has no seizure disorder concerning abnormal brain activity, the term PNES is not used as much. 

The cause of pnee are conditions such as anxiety, depression, panic attacks, and other mental conditions, which result in seizure like activity, only without the chemical effects on the brain that epilepsy has.

It is also possible that an individual can have both epilepsy and pnee, and although the main cause of epilepsy is chemical imbalance of the brain, psychological stresses as depression and anxiety have also been shown to be triggers for not only PNEE, but epileptic seizures as well (6,7,8) although more research may be needed. If you believe you have either pnee or both pnee and epilepsy, you should mention it to your doctor in order to get tests ran.

How do you know ? 

It’s impossible to know the type of event that is occurring unless the individual is being monitored with an EEG, although for the patient, if no after effects are felt, this may be a possible sign of PNEE. The use of therapies like cognitive behavioral therapy, mindfulness, and meditation have been shown to help reduce if not eliminate PNEE due to stress reduction. Because it has been shown that stress can be a possible trigger for epileptic seizures, using therapies for treatment of epileptic seizures may be possible.  Also, since the use of marijuana helps with stress reduction,  it could be an indirect factor in how it assists in  some epileptic seizures, but more research needs to be done.  If you think that stress may be a trigger for seizures, therapeutic treatments and/or CBD/THC may  help in reducing seizure frequency and should be considered.

Forms of marijuana

Smoking:

This is the basic form of smoking marijuana. It is as effective as other methods but may not be the most effective

Vaporization:

Using vaporization to ingest marijuana is similar to smoking, but without the side effects that smoking brings with it. Using vaporizing you see a decrease in byproducts produced when smoking.

Oils

Oils are a simple form of marijuana and can be used in food or added to a drink.

Capsule

Marijuana in capsule form uses the oil of the THC and cbd. Using the pill form of marijuana allows for quick relief.

Side Effects

Marijuana

Drowsiness

Loss of appetite

Sleeplessness

Increased risk of infection

Diarrhea

Medications

Sleep disturbances

Irribility

Dizziness

Memory issues

Slurred speech

Although side effects are normally seen as a negative, some of these side effects could be good. An example of this may be an individual that had a difficult time going to sleep. Someone that has a low appetite level which is a side effect of some epilepsy medications would be helped as well.

Where is it legal ?

There are currently a number of countries which allow the use of marijuana as a medical treatment. Although this does not include the United States, it is legal in some states. Here are the states where marijuana is legal for medical use, as well as other countries.

States

Countries

States

References

1.https://pubmed.ncbi.nlm.nih.gov/30194563/

2. https://pubmed.ncbi.nlm.nih.gov/31372958/

3.https://pubmed.ncbi.nlm.nih.gov/28799512/

4.https://pubmed.ncbi.nlm.nih.gov/28589518/

5.https://pubmed.ncbi.nlm.nih.gov/28494323/

6.https://pubmed.ncbi.nlm.nih.gov/24117321/

7.https://pubmed.ncbi.nlm.nih.gov/16877046/

8.https://pubmed.ncbi.nlm.nih.gov/28063791/.

Notice: This content is meant for general information purposes only in order to assist one in better understanding of how marijuana may help in treating epilepsy. You should first consult with your doctor on how you think this may be of some use before using any of the products mentioned in order to recieve clearance. 

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